Journal: European radiology
This publication is a consensus‑style recommendations paper focused on standardising MRI-based T-staging in prostate cancer to improve prognostic relevance and treatment planning.
Key points:
- Use of “mr” prefix:
- MRI-derived T-stage should be explicitly labeled with the prefix “mr” (e.g., mrT2, mrT3a) to distinguish it from clinical (digital rectal exam–based) and pathological T-staging.
- This is intended to avoid confusion in multidisciplinary discussions and documentation.
- Terminology alignment with pathology/TNM:
- The term “extraprostatic extension” (EPE) is recommended as the official radiologic term, replacing “extracapsular extension,” to align with pathology reports and the UICC TNM system.
- EPE on MRI corresponds to mrT3a disease.
- Subclassification of mrT3a (EPE):
- Radiologists should distinguish:
- “Focal” EPE – limited, small-volume extension beyond the prostate.
- “Established” EPE – more extensive, definite extension.
- Established EPE is associated with a higher recurrence risk and typically warrants more aggressive or less nerve‑sparing surgery and/or intensified radiotherapy strategies.
- Radiologists should distinguish:
- Clinical implications:
- Incorporating the mr-prefix, EPE terminology, and focal/established subclassification into structured MRI reports and tumor board discussions can:
- Refine risk stratification beyond traditional clinical T-stage.
- Better guide nerve-sparing decisions, margin risk assessment, and use of adjuvant or escalated therapies.
- Help reduce both overtreatment and undertreatment.
- Incorporating the mr-prefix, EPE terminology, and focal/established subclassification into structured MRI reports and tumor board discussions can:
- Standardisation and quality assurance:
- The authors emphasize:
- Standardised acquisition protocols for prostate MRI.
- Objective, reproducible criteria for MRI signs of EPE (e.g., measurable and clearly defined features) to minimize inter-reader variability.
- Quality assurance programs and targeted training for radiologists and technologists to improve consistency across institutions.
- The authors emphasize:
Overall, the paper argues that harmonised MRI-based T-staging nomenclature and criteria—particularly the mr-prefix, use of “extraprostatic extension,” and focal vs established EPE subclassification—will make MRI staging more reproducible, clinically actionable, and better integrated into contemporary prostate cancer management.