Prolonged response to dual immune checkpoint blockade in patients with advanced solid tumors: a case series.
This publication reports on five patients with advanced cancers—ranging from microsatellite stable rectal and colon ad...
Optimizing colonoscopy-based colorectal cancer screening by low-barrier, low-threshold pretesting.
- Post category:Digestive (CRC, Stomach) System
- Reading time:1 min read
This study evaluates an innovative "gateopener" colonoscopy-based screening strategy for colorectal cancer (CRC) that em...
Pembrolizumab Plus Chemotherapy Versus Chemotherapy as Perioperative Therapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer: Final Analysis of the Randomized, Phase III KEYNOTE-585 Study.
- Post category:Digestive (CRC, Stomach) System
- Reading time:1 min read
The phase III KEYNOTE-585 trial evaluated neoadjuvant and adjuvant pembrolizumab combined with chemotherapy versus chemo...
Toward Precision Chemotherapy for Pancreatic Cancer Guided by Transcriptomic Signatures.
- Post category:Digestive (CRC, Stomach) System
- Reading time:1 min read
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer treated primarily with chemotherapy, but current regim...
Modified RECIST submodels and ordinal regression model predict neoadjuvant chemoimmunotherapy response in locally advanced gastric cancer.
- Post category:Digestive (CRC, Stomach) System
- Reading time:1 min read
This prospective multicenter study assessed predictive models integrating CT and ultrasound to evaluate neoadjuvant ther...
Inflammation and mutational burden differentially associated with nivolumab or ipilimumab combination efficacy in colorectal cancer.
- Post category:Digestive (CRC, Stomach) System
- Reading time:1 min read
The phase 2 CheckMate 142 study demonstrated durable clinical benefit of nivolumab alone and combined with ipilimumab in...