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Patient-specific sequencing panels enable sensitive circulating tumor DNA analysis in rhabdomyosarcoma independent of genetic profile.

  • Post category:Hematologic Cancers
  • Reading time:1 min read

This study addresses the lack of liquid biomarkers for monitoring rhabdomyosarcoma by developing a tumor-informed circul...

Continue ReadingPatient-specific sequencing panels enable sensitive circulating tumor DNA analysis in rhabdomyosarcoma independent of genetic profile.

Multimodal prediction of metastatic relapse using federated deep learning in soft-tissue sarcoma with a complex genomic profile.

  • Post category:Hematologic Cancers
  • Reading time:1 min read

This study presents SarcNet, a multimodal deep-learning algorithm integrating histological whole-slide images and clinic...

Continue ReadingMultimodal prediction of metastatic relapse using federated deep learning in soft-tissue sarcoma with a complex genomic profile.

Efficacy and Safety of Trametinib Therapy for Complex Lymphatic Malformations.

  • Post category:Hematologic Cancers
  • Reading time:1 min read

This study assessed trametinib in five pediatric patients (median age 9) with complex lymphatic malformations, including...

Continue ReadingEfficacy and Safety of Trametinib Therapy for Complex Lymphatic Malformations.

Neoadjuvant immunotherapy in mismatch-repair-proficient colon cancers.

  • Post category:Hematologic Cancers
  • Reading time:1 min read

This phase II NICHE study evaluated neoadjuvant immune checkpoint blockade (nivolumab plus ipilimumab) in 31 patients wi...

Continue ReadingNeoadjuvant immunotherapy in mismatch-repair-proficient colon cancers.

High-dose busulfan-melphalan vs melphalan and reinforced VRD for newly diagnosed multiple myeloma: a phase 3 GEM trial.

  • Post category:Hematologic Cancers
  • Reading time:1 min read

This phase 3 GEM12 trial evaluated long-term outcomes of autologous stem cell transplantation (ASCT) conditioning with b...

Continue ReadingHigh-dose busulfan-melphalan vs melphalan and reinforced VRD for newly diagnosed multiple myeloma: a phase 3 GEM trial.

Treatment of transplant-ineligible multiple myeloma.

  • Post category:Hematologic Cancers
  • Reading time:1 min read

This publication reviews the evolving treatment landscape for transplant-ineligible multiple myeloma (MM) patients. It h...

Continue ReadingTreatment of transplant-ineligible multiple myeloma.
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