Artificial Intelligence in Low-Dose Computed Tomography Screening of the Chest: Past, Present, and Future.

Journal: Journal of thoracic imaging

This publication reviews the integration of artificial intelligence (AI) with low-dose computed tomography (LDCT) in lung cancer screening, highlighting its evolution over more than 30 years through the International Early Lung Cancer Action Program (I-ELCAP).

It outlines key advances in AI, including:

  • Lung nodule detection
  • Emphysema quantification
  • Cardiovascular risk assessment

The review emphasizes the development of the open-source IELCAP-AIRS system and the ScreeningPLUS infrastructure for AI training and deployment.

The paper also addresses challenges such as imaging variability and clinical integration, while underscoring AI’s potential to:

  • Reduce radiologist workload
  • Enable precise disease quantification
  • Broaden screening to multiple diseases from a single LDCT scan

Finally, the authors stress the importance of collaboration, standardized protocols, and large datasets to advance AI-driven, preventive care.

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