Development of a questionnaire to assess the medication literacy of patients receiving oral anticancer drugs.

Journal: Scientific reports

This publication reports the development and initial validation of a questionnaire to measure medication literacy in patients receiving oral anticancer therapy.

Design and development:

  • Semi-structured patient interviews and an expert focus group were used to generate questionnaire content.
  • The initial instrument had two parts, each with four dimensions:
    • Part A: self-assessed medication literacy.
    • Part B: functional medication literacy.
  • The draft was tested in a survey conducted in oncology practices and community pharmacies.

Psychometrics and structure:

  • Factor analysis yielded a final instrument with 27 items across 7 dimensions.
  • 307 patients on oral anticancer agents participated.
  • Mean scores:
    • Part A: 36.7/50.
    • Part B: 11.7/17.
  • Higher scores represented better medication literacy.
  • Part A demonstrated acceptable psychometric properties.
  • Part B showed insufficient internal consistency and requires further refinement.

Clinical relevance:

  • Higher self-assessed medication literacy (Part A) was positively associated with quality of life and patient enablement.
  • The self-assessment component could serve as:
    • A patient-reported outcome measure in clinical and implementation studies.
    • A screening tool to identify patients needing additional support with their oral anticancer medications.
  • The functional literacy component is not yet ready for routine use and needs methodological improvement.

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