Influence of B cell-lineage targeted CAR-T cell therapy on humoral immunity and vaccine-induced antibody response.
This prospective study followed 128 patients with hematologic malignancies receiving CAR T-cell therapy targeting CD19,...
Global access to commercial CAR T-cell therapies: a cross-sectional study of health technology assessment across the G20 countries.
- Post category:Hematologic Cancers
- Reading time:2 mins read
This study is a cross-sectional analysis of how national health technology assessment (HTA) bodies in major economies ev...
Patient-reported health-related quality of life in previously untreated chronic lymphocytic leukaemia: Results from the randomised phase 3 FLAIR trial comparing ibrutinib-rituximab versus fludarabine-cyclophosphamide-rituximab.
- Post category:Hematologic Cancers
- Reading time:2 mins read
Phase 3 FLAIR trial patients with previously untreated CLL (age 18–75, PS ≤2, no >20% del(17p)) were randomized to i...
Gotistobart or docetaxel in metastatic squamous non-small cell lung cancer: stage 1 of the randomized phase 3 PRESERVE-003 trial.
- Post category:Hematologic Cancers
- Reading time:2 mins read
This publication reports stage 1 results of PRESERVE-003, a two‑stage phase 3 trial testing gotistobart (BNT316/ONC‑...
Comparable outcomes of HSCT up-front and after failure of IST in pediatric aplastic anemia in recent years.
- Post category:Hematologic Cancers
- Reading time:2 mins read
Study type - Retrospective analysis of 179 children with severe aplastic anemia undergoing allogeneic HSCT. Cohorts...
Significant clinical impact of immunosuppressive therapy termination after allogeneic haematopoietic stem cell transplantation.
- Post category:Hematologic Cancers
- Reading time:1 min read
This retrospective registry study evaluated the impact of stopping systemic immunosuppression within 2 years after allog...