Trabectedin and low-dose irinotecan to target EWS::FLI1 in Ewing sarcoma: a phase 1/2 trial.
Phase 1/2 trial design - Population: 37 patients with relapsed/refractory Ewing sarcoma. - Regimen: Trabectedin as a...
The role of the molecular tumor board: learnings from the ROME trial.
- Post category:Supportive Oncology
- Reading time:2 mins read
This publication reports on the Phase II ROME trial, a randomized study assessing whether treatment selection guided by...
Disruptive Analysis of Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer: Clinical and Therapeutic Distinctions Between Low- and Mid-Rectal Cancers.
- Post category:Supportive Oncology
- Reading time:2 mins read
This publication is a narrative review examining how tumor location within the rectum should influence the use and inten...
Comprehensive analysis of FGFR2b and its correlation with essential biomarkers, intratumoral heterogeneity, and survival in advanced gastric cancer.
- Post category:Supportive Oncology
- Reading time:2 mins read
This study evaluated FGFR2b protein expression in a large real‑world cohort of 1331 patients with locally advanced or...
Real-world clinical utility of tumor whole-genome sequencing in solid cancers.
- Post category:Supportive Oncology
- Reading time:2 mins read
This study reports real-world implementation of routine paired tumor–normal whole-genome sequencing (WGS) for solid tu...
High-sensitivity pan-cancer AI assessment of lymph node metastasis via uncertainty quantification.
- Post category:Supportive Oncology
- Reading time:2 mins read
This study describes UPATHLN, a pan-cancer AI system for detecting lymph node metastases on pathology slides, with a spe...