Autocatalytic Signal Amplification via Orthogonal Recognition of Dual Proteins on the Surface of Serum Extracellular Vesicles for Precise Diagnosis of Prostate Cancer.

This study presents a novel dual-protein orthogonal triggered autocatalytic signal amplification (DOTASA) strategy to im...

Continue ReadingAutocatalytic Signal Amplification via Orthogonal Recognition of Dual Proteins on the Surface of Serum Extracellular Vesicles for Precise Diagnosis of Prostate Cancer.

Niraparib and abiraterone acetate plus prednisone for HRR-deficient metastatic castration-sensitive prostate cancer: a randomized phase 3 trial.

The AMPLITUDE trial investigated the efficacy of adding niraparib, a PARP inhibitor, to abiraterone acetate and predniso...

Continue ReadingNiraparib and abiraterone acetate plus prednisone for HRR-deficient metastatic castration-sensitive prostate cancer: a randomized phase 3 trial.